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Mar 10, 2011 – Compounds that inhibit the S. aureus SrtA sortase may function as potent . Many of these molecules also inhibit the sortase enzyme from B. .

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Jun 4, 2010 – Streptococcus uberis, strain 0140J, contains a single copy sortase A (srtA), encoding a transamidase capable of covalently anchoring specific .

'On the role of Staphylococcus aureus sortase and sortase-catalyzed surface protein anchoring in murine septic arthritis.' on BiomedExperts.

The Staphylococcus aureus sortase is a transpeptidase that attaches surface proteins to the cell wall; it cleaves between the Gly and Thr of the LPXTG motif and .

Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of . Cleavage of this FRET substrate by sortase reveals the fluorescent signal, .

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Abstract Abstract: Creation of functional protein bioconjugates demands methods for attaching a diverse array of probes to target proteins with high specificity, .

Note About: Tus-Tweezers_experiment In November I am doing an experiment with Andy Ward at the LSF where our aim is to do single molecule studies of Tus .

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Nov 18, 2007 – In a recent post I extolled the possible virtues of Open Notebook Science in avoiding or ameliorating the risk of being scooped. I also made a .

Sortase refers to a group of prokaryotic enzymes which catalyze the assembly of pilins into pili, and the anchoring of pili to the cell wall. They act as both .

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Rabbit polyclonal to Sortase A primary antibody datasheet (ab13959).

Oct 19, 2011 – Sequence or UniProt identifier. >tr|Q9S446|Q9S446_STAAU Sortase OS= Staphylococcus aureus GN=srtA PE=1 SV=1 .

putative sortase substrates of Bacillus anthracis Ames 0581. gene identifier. cell wall sorting signal. length, SP. gi_47525668 .

In Gram-positive bacteria, many surface proteins are covalently anchored to .

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Modification of proteins with small molecules is a widely used and powerful tool in biological research. Enzymatic approaches are particularly promising .

#=GF ID Sortase #=GF AC PF04203.7 #=GF DE Sortase family #=GF AU TIGRFAMs, Finn RD #=GF SE TIGRFAMs (release 2.0); #=GF GA 21.30 21.30; #=GF TC 21.40 21.30; .

Nov 7, 2008 – The Sortase A enzyme of S. aureus provides an effective means of ligating a range of molecules to the C-termini of proteins. Sortase can be .

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Hospital-borne bacterial infections present a major challenge in patient care due to the rising number of strains resistant to multiple antibiotics in recent years.

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Query Choose genomes to view sortases and sortase substrates. . You can classify a given sortase homolog by running the following command using HMMER .

Mar 10, 2011 – Whitehead Institute scientists have created a method that site-specifically modifies proteins to exert control over their properties when .

Information on EC 3.4.22.70 - sortase A. . sortase A transpeptidase, Staphylococcus aureus, -, 665718. sortase SrtA, Staphylococcus aureus, -, 691247. sortase .

5+ items – David Bulger's Presentation at The Oklahoma Academy of .

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Mar 1, 2001 – A major mechanism for the surface display of proteins by Gram-positive bacteria is sortase-mediated covalent attachment to the cell wall. .

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Sortase A (srtA) is a sequence-specific transpeptidase found in S. aureus and other Gram-positive bacteria. The S. aureus enzyme recognizes an LPXTG site ( X .

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A Comparative Genome Analysis Identifies Distinct Sorting Pathways in Gram- Positive Bacteria.

File:Sortase.png. From Wikipedia, the free encyclopedia. Jump to: navigation .

HUBZone-Owned: No. Phase 1. Fiscal Year: 2005. Title: Novel one-step purification with a sortase fusion. Agency: HHS. Contract: 1. Award Amount: $100000.00 .

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