Mechanism of action of nalidixic acid: purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing .

Dna Gyrase; DNA Gyrase A Subunit; DNA Gyrase B Subunit; gyrA Protein; gyrB Protein. On-line free medical diagnosis assistant.

7 posts - 3 authors - Last post: May 3, 2007In order to understand this concepts of positive/negative supercoiling and DNA gyrase, you need to have an understanding about the following .

In combination with topoisomerase I, which eliminates negative supercoils, DNA gyrase affects the degree of supercoiling of the bacterial chromosome. .

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DNA topoisomerases are enzymes that control and modify the topological states of DNA in cells. Bacterial DNA gyrase is a type II DNA topoisomerase which .

5 posts - 5 authors - Last post: Apr 8, 2010Definition and other additional information on Dna gyrase from Biology-Online. org dictionary.

Oct 30, 2008 . A method for inhibiting bacterial DNA gyrase in a warm-blooded animal, such as a human being, in need of such treatment which comprises .

Apr 5, 2011 . DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP- dependent manner and also catalyzes the interconversion of .

by RJ Reece - 1991 - Cited by 364 - Related articles

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TOPOGEN-S. Aureus DNA Gyrase - Available from TopoGEN.

This enzyme can thus decatenate circular duplex DNA. All type II enzymes can relax both positively and negatively supercoiled DNA. Bacterial DNA gyrase is a .

by HS Cho - 2004 - Cited by 34 - Related articles

Mouse monoclonal [7F11] to DNA Gyrase A primary antibody datasheet (ab75592).

by M Tanaka - 1996 - Cited by 9 - Related articles

Biology question: How do DNA gyrases and helicases differ in their respective functions and modes of action? Helicases are involved in the unwinding of DNA .

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by M Nöllmann - 2007 - Cited by 29 - Related articles

DNA gyrase, often referred to simply as gyrase, is an enzyme that relieves strain while double-stranded DNA is being unwound by helicase. .

by G Condemine - 1990 - Cited by 27 - Related articles

SbmC is an inhibitor of DNA gyrase-mediated DNA supercoiling [ Nakanishi98 ] that inhibits the enzyme activity at an early step [ Chatterji02 ]. .

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by EM Bahassi - 1999 - Cited by 46 - Related articles

Quinolone drugs can inhibit bacterial DNA replication, via interaction with the type II topoisomerase DNA gyrase. Using a DNA template containing a .

DNA gyrase is the topoisomerase uniquely able to actively introduce negative supercoils into DNA. Vital in all bacteria, but absent in humans, .

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Mainly antiparallel beta sheets (segregated alpha and beta regions); Fold: Putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) [111282] .

Topoisomerase II (called gyrase in bacteria) primarily introduces negative supercoils into DNA. In bacteria, topoisomerase II consists of two polypeptide .

DNA gyrase (ji´rās) a type II DNA topoisomerase. DNA gyrase,. an enzyme that nicks and seals the DNA and relieves supercoiling. DNA. deoxyribonucleic acid. .

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by K Drlica - 1997 - Cited by 630 - Related articles

3 answers - Apr 22, 2007I've searched around and I just couldn't find a simple explanation . During replication, DNA gyrase moves ahead of DNA helicase to relieve the .

Mechanism of DNA Gyrase. In a relatively short period of time, large advances have been made in the determination of DNA gyrase mechanisms, yet the complete .

A nucleic acid that carries the genetic information in the cell and is capable of self-replication and synthesis of RNA. DNA consists of two long chains of .

Jan 1, 2003 . Objective To study the gyrA mutation of clinical Pseudomonas aeruginosa strains. Methods By determing the MIC value, one sensitive strain .

Jul 26, 2004 . DNA gyrase . SYN: nickase, swivelase. A topoisomerase that relieves supercoiling in DNA by creating a transient break in the double helix. .

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Feb 17, 2011 . very good explanation, i have a much better understanding on DNA Gyrase. Thank you! cmmccul2 3 months ago. View all Comments » .

by A Maxwell - 1993 - Cited by 161 - Related articles

Jun 10, 2010 . DNA Gyrase from E.Coli is an enzyme belonging to the class of Topoisomerases, which allows the organism to modify the topology of its DNA. .

Apr 29, 2011 . DNA gyrase information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.

DNA Gyrase (E. coli) is a Type II topoisomerase that catalyzes the introduction of negative supercoils in DNA in the presence of ATP. The gyrase holoenzyme .

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Aug 12, 2010 . The present invention provides methods and compositions useful for in vitro polypeptide synthesis reactions. The methods involve the use of .

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'The interaction of drugs with DNA gyrase: a model for the molecular basis of quinolone action.' on BiomedExperts. Find the right expert or researcher in .

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