We propose that ribosomes translating IF3 disrupt the pseudoknot and thereby

large ribosomal subunit in the regulation of membrane affinity and provides a

If we assume strong affinity of mRNA to ribosome. it is quite understandable that

Translational coupling has been observed in both phages [1, 2] and in bacteria

We have examined the translational coupling between the first .

The mechanism of translational coupling in repBA was investigated using the

May 10, 2011 . translational coupling, Prokaryotes can keep ribosome on transcript by using

Nov 20, 1992 . Although translational coupling in ribosomal protein operons has been

reinitiation is an extreme case of translational coupling in which translation of a

secondary promoters (Zengel and Lindahl, 1994). One mechanism that

is disrupted by a ribosome translating the upstream coding region. (Below). This

. of the spc operon in Escherichia coli: translational coupling and mRNA

of the translation of their own mRNAs, so that the synthesis of r-proteins is

REGULATION OF TRANSLATIONAL GENES Regulation of Ribosomal . site for

A somewhat special ease with respect to translational coupling is found in the

The start of the L cistron is not directly accessible to ribosomes. Instead its

bound ribosome and translocating nascent chain, detailed hypotheses regarding

Jul 2, 2004 . ANSWER: Coupling of transcription and translation means that ribosomes bind to

can be controlled by translational coupling, translation repression, or premature

a region overlapping the ribosome binding site, called the translational operator.

The EMBO Journal encourages and publishes articles that report novel findings

The exact mechanism of translational coupling is not clearly understood,

Apr 23, 2010 . Acceleration and deceleration of a ribosome result in corresponding changes .

Mutational alterations of translational coupling in the L11 ribosomal protein

Mar 1, 2011 . most likely reflects translational coupling and allows us to identify other putative

hibit translation, but not to mediate tight coupling. Re- sults obtained using the “

ORFs and the ribosome binding sites (RBSs) involved, the optimal configuration

Key words: Translational coupling - penP-lacZ gene fusion. - Bacillus subtilis . ..

5' ribosome, where normal release is thought to occur. . TRANSLATIONAL

structure provides enough time for ribosomes to access the RBS and facilitates

Translational coupling was demonstrated in a gene fusion in which the promoter

The mechanism of translational coupling at the nifLA operon was analysed using

We have examined the translational coupling between the first two genes in the

(1996) Chiaruttini et al. Biochimie. The Escherichia coli IF3-L35-L20 operon

(2000) Inokuchi et al. the The European Molecular Biology Organization Journal.

The EMBO Journal encourages and publishes articles that .

Translational Coupling The fully independent translation initiation of different .

stem–loop structure, which is one of the criteria allowing the translation of. repA

ribosome assembly, act as translational feedback inhibitors on their polycistronic

Most polycistronic mRNAs indeed have one Ribosome binding site for each . It

The complete ribosome (80S) then commences translation elongation, . This

We propose that ribosomes translating IF3 disrupt the pseudoknot and thereby

Jul 17, 2000 . Depending on the origin of the ribosomes that translate the coupled downstream

Alternatively, close spacings may be preferred because of translational coupling

However, when ribosomes begin translation at the rbs and AUG of the upstream

oligonucleotide-directed mutagenesis. (translational repression/translational

The translational coupling of the coat and lysis gene of phage fr was shown to be

Jul 8, 1994 . The mechanism of translational coupling in Escherichia coli. . as a

Mutational alterations of translational coupling in the L11 ribosomal protein

In the absence of such translational coupling, the ribosome recycling factor

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