In the rough endoplasmic reticulum (RER)the alpha and beta chains associate

Search Criteria: Research Area is "Immunology and Inflammation Research:

The major histocompatibility complex class II associated invariant chain (Ii) has

Inhibition of invariant chain expression (CD74) in DCs incubated with antisense

processed antigen is determined by the invariant chain. (li). By analysis of . the

CD74 molecule, major histocompatibility complex, class II invariant chain . The

The invariant chain (Abbreviated Ii) is a polypeptide involved in the formation and

Jan 6, 2008 . or the transfection of cells with genes or minigenes encoding the antigen of

The CD74 antigen (also known as H-2 class II histocompatibility antigen gamma

The invariant chain (I chain) associates with major histocompatibility complex

ABSTRACT: The murine invariant chain (Ii) was found to incorporate radioactive

and Jacobson, 1989; Koch et al., 1989). Class II molecules assemble in the

The SCOP classification for the Class II MHC-associated invariant chain

The MHC class II-associated invariant chain (Ii) has several important functions in

A fragment of the invariant chain, CLIP, occupies the peptide-binding groove of

Differentially Expressed MHC Class II-associated Invariant Chain in Rat Stomach

invariant chain (Ii). The I-class H association has been shown to block peptide-

May 19, 2011 . The invariant chain is associated with MHC class II (and recently shown to be

In antigen presenting cells, the assembly of matched α and β subunits to

Use the filters to narrow your HLA-DR antigens-associated invariant chain

absence of invariant chain, intracellular a13 heterodimers could be detected .

Invariant Chain Fragment Is a Strong Inhibitor of Lysosomal . The invariant chain

May 16, 2011 . Requirement for invariant chain in macrophages for Mycobacterium tuberculosis

ABSTRACT. The invariant chain (Ii) is a glycoprotein coexpressed with the major

Dec 1, 2007 . A revised model for invariant chain-mediated assembly of MHC class II peptide

The invariant chain (Ii; CD74) plays a critical role in this process by influencing

The invariant chain also facilitates the export of class II MHC from the ER to the

3 days ago . Soluble invariant chain lacking the transmembrane region forms a trimer. .

Abstract. The invariant chain (Ii) is a key player in regulating the MHC Class II

Invariant chain (Ii) and HLA-DM molecules are implicated in the antigen

The invariant chain (Ii)-derived peptide CLIP is required for HLA-II-mediated

Invariant Chain and the MHC Class II Cytoplasmic Domains. Regulate

class II molecules at the cell surface depends critically on the invariant chain. (Ii).

Found a total of 67 Ia antigen-associated invariant chain antibodies from 5

Feb 27, 2012 . Differential regulation of MHC II and invariant chain expression during maturation

of the class ll-associated invariant chain. These peptides were rare on DR3 . II-

for a pool of excess invariant chain in class H-positive cells, suggesting that an .

The p41 isoform of invariant chain is a chaperone for cathepsin L. Ana-Maria

general model of invariant chain association, indicating that it binds to all class II

the invariant chain on the cell surface is very similar to that of class II molecules,

In addition to functioning as an MHC class II chaperone, Cd74 was required for B

(1984) Koch et al. The Journal of Immunology. Metabolic labeling and

milatuzumab, which targets the invariant chain . Introduction: Targeting CD74 as

. Encyclopedia, Wikipedia, 0.01 sec. Acronym, Definition. CLIP.acronyms.thefreedictionary.com/Class+II-associated+invariant+chain+peptide - Cached - SimilarThe intracellular localization and oligomerization of chicken . Invariant chain (Ii) binds to MHC class II (MHCII) to assemble a nonamer in the

May 26, 2006 . Ia associated invariant chain - Medical Terms is a service who provides

Class II-associated invariant chain peptide down-modulation enhances the

Mar 21, 2012 . HLA-DR antigens-associated invariant chain. Ia antigen-associated invariant

S tepwise degradation of the invariant chain (Ii) is required for the binding of

Aug 9, 2010 . Abstract. Background— Adaptive immunity and innate immunity play important

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