Sep 26, 2011 . Effects of inducers or inhibitors of autophagy and apoptosis combined with

May 28, 2005 . inhibition of autophagy reversed these effects and rescued cell viability. We

Mar 4, 2011 . Verteporfin is a benzoporphyrin derivative used in photodynamic therapy, but it

Apr 2, 2010 . This article provides a detailed analysis of the temporal function of two widely

In this study, we investigated whether or not 3-methyladenine (3-MA), which is a

METHODS: Two colon-cancer-derived cell lines, colon26 and HT29, were used

mTORC1 inhibition and autophagosome accumulation induced by perhexiline,

Oct 28, 2011 . Inhibition of autophagy enhances cisplatin cytotoxicity through endoplasmic

Oct 13, 2011 . Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death .

Buy Autophagy Inhibitor, 3-MA (CAS 5142-23-4), an autophagic sequestration

Therefore, inhibition of autophagy could maintain continuous tumour growth.

Inhibition of autophagy: a new strategy to enhance sensitivity of chronic myeloid

Sep 13, 2011 . microRNA-101 is a potent inhibitor of autophagy. Frankel LB, Wen J, Lees M,

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in

Jul 4, 2003 . We have used a panel of inhibitors/stimulators of autophagy and proteasome

Dec 1, 2007 . The role of mETC inhibitors in autophagy-induced cell death is unknown. Herein,

Mar 1, 1982 . 3-Methyladenine (5 mM) inhibits endogenous protein degradation in . suggests

Tributyltin chloride (TBT) is a neurotoxic environmental pollutant that inhibits

We showed that the dual PtdIns3K-mTOR inhibitor PI-103 induces autophagy in

Autophagy requires PI3K but is negatively regulated by mTOR. Thus inhibitors of

with the classical inhibitor of autophagy 3MA (Blom- . . tional inhibitors of

Jun 13, 2011 . Detached retinas had increased levels of autophagosome-associated lysosomal

Jul 1, 2009 . The autophagy inhibitor 3-MA partially suppresses neuronal cell loss caused by

Paclitaxel has been demonstrated to be an effective mitotic inhibitor and

Rapamycin, an inhibitor of mTOR, induces autophagy. The PTEN gene mutation

in response to treatment with lysosomal protease inhibitors or pharmacological

Apr 28, 2009 . ite increases NB4 cell apoptosis by autophagy inhibition through. PI3K/Akt, and

Here, we show that the AP-1 proteins JunB and c-Jun, but not JunD, c-Fos, or Fra

Dec 10, 2010 . Chloroquine and its analog hydroxychloroquine are the only clinically relevant

Jun 6, 2011 . Inhibition of autophagy by autophagy inhibitors or siRNA, cholangiocarci- noma

Lysosomal inhibitors and 3-methyladenine, an inhibitor of autophagy, stabilized

Inhibitors of Autophagy. KEVIN V. ROTE* AND MARTIN RECHSTEINER.

Sep 13, 2011 . Importantly, overexpression of STMN1 could partially rescue cells from miR-101-

Identification of Novel Autophagy Inhibitors [Signal Transduction] Friday,

Dec 3, 2009 . 2183 An Autophagy Inhibitor, Chloroquine, Overcomes An Imatinib-Resistant

Oct 6, 2008 . Autophagy inhibitors deliver a knock-out blow. Richard Robinson. rrobinson/at/

Sigma-Aldrich Online Catalog Product List: Autophagy Inhibitors.

To test the hypothesis that therapy-induced autophagy is a survival strategy for

The results showed that autophagy inhibition effectively enhanced cell killing

TOR complex 1 (TORC1), which is known to be active in LAM cells, is a key

Autophagy is a homeostatic mechanism of lysosomal degradation. Defective

Titre du document / Document title. The inhibition of autophagy potentiates anti-

Feb 1, 2007 . Inhibition of autophagy with either chloroquine or ATG5 short hairpin RNA (

Nov 9, 2010 . Inhibitors of autophagosome maturation cooperated with PI-103 to induce . Not

Jul 29, 2011 . Inhibition of the mTOR signaling pathway promotes initiation of autophagy.

Oct 6, 2008 . Akt knockdown or inactivation with small molecule inhibitors did not induce

May 1, 2009 . Critically, the combination of a tyrosine kinase inhibitor (TKI), i.e., IM, nilotinib, or

Oct 1, 2010 . AMPK/p21 signaling caused endoplasmic reticulum (ER) stress response

Title: Inhibition of autophagy in mitotic animal cells. Author: Lucocq, John; Backer,

Mar 15, 2011 . Inhibition of autophagy in PDAC cell lines attenuates growth and tumorigenicity

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