Mar 16, 1999 . This duplication and subsequent segregation in mitosis results in maintenance of

Access an online audio visual presentation by Prof. Andrew Fry on Centrosome

Before we can discuss centrosome duplication, we . paradigms for centrosome

Centrosome amplification occurs when the mechanisms that regulate

Jan 23, 2009 . name: negative regulation of centrosome duplication namespace:

(2006) Tsou, Stearns. Nature. Read by researchers in: 97% Biological Sciences,

Centrosome amplification occurs when the mechanisms that regulate

However, little is known about the role of Pinl in centrosome duplication and the

Jan 22, 2002 . Like DNA, the centrosome must be duplicated once and only once during each

1) Cell cycle control of centrosome duplication. We have shown that duplication

Here, we report the first known function of a mammalian NDR kinase by

The yeast Mps1p protein kinase acts in centrosome duplication and the spindle

duplication of the centrosome is a poorly understood process. Three recent

The replication of a centrosome, a structure comprised of a pair of centrioles and

Durcan TM. Centrosome duplication proceeds during mimosine-induced G1 cell

Oct 3, 2011 . We discuss spatial aspects of the centrosome duplication cycle, the mechanism

Jul 12, 2011 . In collaboration with german researchers, the group of Pierre Gönczy (SV ISREC

I previously demonstrated that vertebrate Mps1 proteins are required for

each daughter cell inherits a single centrosome, duplication of which is initiated

Therefore, it is important to understand the molecular mechanisms that drive

"SAS-6 defines a protein family required for centrosome duplication in C. Elegans

centrosome duplication, cell division, and cytokinesis. Elizabeth S. . major

During the cell division cycle, duplication of the centrosome and segregation of

Here, we outline a number of fluorescence imaging methodologies that can be

The authors reviews publications on the centrosome, a microtubule organizing

Control of centrosome duplication is exercised by limits that are intrinsic to the

recently been shown that centrosome duplication in vertebrates requires Cdk2 .

Sebastian Leidel, Pierre Gonczy. International Worm Meeting (2003).

all restore the normal process of centrosome duplication to zyg-1 mutants. .

Jul 13, 2001 . It has recently been shown that centrosome duplication in vertebrates requires

In Caenorhabditis elegans, the kinase ZYG-1 is required for centrosome

Mechanism limiting centrosome duplication to once per cell cycle. - MSKCC.

The duplication of the centrosome is a key event in the . responsible for

Aberrant centrosome duplication is observed in many tumor cells and may con-

Feb 12, 2011 . Centrosome duplication is the replication of a centrosome, a structure comprised

VASCULAR BIOLOGY. Angiogenic factor signaling regulates centrosome

The duplicated centrosomes accumulate additional pericentriolar material prior to

Our findings indicate that Cdc25A S123 phosphorylation is crucial for coupling

Who controls centrosome duplication? In: Bioscience. 5 The transition between

Aug 24, 2006 . Cells begin the cell cycle with a single centrosome, which duplicates once before

Jul 13, 2007 . The centrosome is duplicated only once per cell cycle so that each daughter cell

hMps1 (hMps1KD) can prevent centrosome duplication in a variety of cell types,

Roles of BRCA1 in centrosome duplication. (PMID:12214252). Abstract; Citations

In cell biology, the centrosome is an organelle that serves as the main

Centrosomal abnormalities are frequently observed in cancers and in cells with

blocks centrosome duplication altogether. . centrosome duplication by mMps1p

Mol Cell Biol. 2006 Feb;26(4):1463-79. Pin1 regulates centrosome duplication,

The centrosome has profound effects on mitotic spindle formation; therefore,

Mar 1, 2003 . The mechanisms governing centrosome duplication remain poorly understood.

Part of, GO:0007099, centriole replication. Regulates, GO:0010824, regulation of

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