Jul 5, 2011 . The centromere is a specialized region of the chromosome, on which a protein .

Chromosome Doubling vs DNA Synthesis. Splitting . During prophase, protein

Comprising 125 base-pairs of CEN DNA and 70 or more protein components,

Jul 16, 2002 . anaphase onset require or contribute to the depletion of kinetochore and

Nov 16, 2011 . >sp|O43264|ZW10_HUMAN Centromere/kinetochore protein zw10 homolog OS=

appeared as two small spheres at the centromere, resembling kinetochores. The

'Kinetochore geometry defined by cohesion within the centromere.' on

No incidence of merotelic attachments or stretched centromere chromatin was

Chromatid; Chromonema or Chromonemata; Chromomeres; Primary constriction

haps the most conserved of all known kinetochore proteins is centromere-specific

tin into motile centromere-kinetochore fragments that contain CENP-A with little

checkpoint — exists at kinetochores, which enforces this grip between sister

(a) The goal of cell division typically is to equally partition two more-or-less . .. (a)

In the past year, I've come across a new hypothesis that states that the

of the kinetochore or its associated corona. Detection of Centromere/Kinetochore

Centromere are protein fibers located in the cytoplasm of a cell. They become

Differential kinetochore protein requirements for establishment versus

Feb 21, 2003 . Forgotten User Name or Password? . Kinetochores are assembled on

fined the centromere (cf. Chapter A) and this term almost immediately became an

movement relative to the sister kinetochore and bulk of the chromosome arms. To

Disruption of centromere assembly during interphase inhibits kinetochore .

Bacterial centromeres and kinetochore complexes . 1. a centromere-like site on

Sep 15, 2011 . The constitutive centromere protein cenp-c and the microtubule-binding

Mar 17, 2003 . Differential kinetochore protein requirements for establishment versus

Apr 16, 2009 . This physical separation or resolution of sister centromeres would be important

Sep 1, 2011 . 2002), or deletion of SPT4 (Crotti and Basrai 2004) result in declustering of

Further support for a re- peat subunit model was obtained by stretching or un-

Enter question or phrase. . Centromere is the 'waist' of a chromosome. .

KINETOCHORE: C-LOOP TOPOLOGY. Cohesin Rings. C-Loop. Kinetochore-

Errors in centromere or kinetochore function are catastrophic for cells. Such

functional, or active, centromere while other centromeres are non-functional or

newly identified centromere components precisely. The localization problem.

GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere

Serum E.K. crossreacts with an 80-kD protein in mouse cells and detects the

centromere (7) and for the correct attachment of the chromo- somes to the spindle

Models of the condensin loss mediated centromere and kinetochore dysfunction.

XXXOriginal Articles. Condensin and centromere. V Yong-Gonzalez et al.

Dec 4, 2011 . Elucidating kinetochore structure remains a fundamental goal in . in vivo, Ndc10

We speculate that either unduplicated centromeres or closely localized

In humans, the primary centromeric repeat unit is called α-satellite (or alphoid), .

Defects in sister kinetochore disjunction could arise if Incenp and/or Aurora B

The kinetochore, an essential multiprotein complex assembled on mitotic or

1.5 Centromere Proteins Well before the yeast geneticists or biochemists

the centromere (Figure 2B). A second CDE II interacting with both core

dynamics and/or a destabilizer of incorrect kinetochore–MT attachments. MCAK

The kinetochore forms in eukaryotes, assembles on the centromere and links the

17. Cohesin is defining kinetochore orientation 18. Rec8 vs. Rad21 at the

Nov 22, 2010 . This review has focused on Aurora B in the context of inter-kinetochore tension,

exercise orderly segregation without causing bridges and/or . . antibody binds

Aug 24, 2009 . The kinetochore, an essential multiprotein complex assembled on mitotic or

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