Synonym: m-Cl-CCP CCCP Mesoxalonitrile 3-chlorophenylhydrazone . (H+

Sustained mitochondrial damage and BVDV in the 65 µM. CCCP treatment group

Jan 26, 2010 . When HeLa cells are treated with CCCP, which depolarizes mitochondria by

Nov 29, 2010 . After 4 h incubation with or without 10 µM CCCP, mitochondria were isolated,

An uncoupling protein is a mitochondrial inner membrane protein that can .

Jan 5, 2010 . HeLa cells were incubated with vehicle (DMSO) or with 10 μM CCCP for 1 h

ADP and CCCP -induced increases in mitochondrial free Ca2+: greater

Antimycin and antimycin + oligomycin had the same effect as CCCP. Active

Cell swelling may contribute to acute cell injury subsequent to ischemia/

Antimycin and antimycin + oligomycin had the same effect as CCCP. Active

CDC, the mitochondrial toxin CCCP and DOG/IAA markedly inhibited both

Abstract 410: Mitochondrial Uncoupling with CCCP Reverses Acute

Oct 1, 2004 . Inhibitors of mitochondria Ca2+ uptake such as protonophore CCCP potentiate

Nov 1, 2005 . The mitochondrial protonophore carbonyl cyanide m-chlorophenylhydrazone (

May 9, 2002 . Because CCCP abolished mitochondrial respiratory control while it was intact in

example with the protonophore CCCP (Ishihara et al., 2003). Induced fission can

Jul 13, 2011 . Parkin mediates mitophagy after prolonged dissipation of the mitochondrial

Feb 21, 2003 . The protonophore, carbonyl cyanide m-chlorophenylhydrazone (CCCP), led to

Apr 19, 2010 . Mitochondrial localization of Parkin is etiologically important. (A) HeLa cells

Detect Mitochondrial Depolarization and Membrane Permeability Transition with

not; this suggests different mechanisms for cytochalasin D and CCCP and a

May 12, 2010 . CCCP is a proton ionophore that destroys the membrane potential across the

May 20, 2011 . disrupter, CCCP (carbonyl cyanide 3-chlorophenylhydrazone), for the study of

The MitoProbe JC-1 Assay Kit (M34152) provides the cationic dye JC-1 and a

Sep 3, 2010 . Nix promoted CCCP-induced mitochondrial depolarization and reactive . . CCCP

Once inside, JC-1 will redistribute itself within healthy polarized mitochondria in a

Dec 1, 2002 . (A) In the presence of cccp, mitochondria loose their tubular morphology and

drial respiration, caused rapid cell killing that was reversed by fructose. CCCP

Aug 10, 2001 . The protonophore CCCP induces mitochondrial permeability transition without

With intact mitochondria, CCCP enters in the protonated form, discharging the pH

Jan 24, 2010 . HeLa cells transfected with HA–Parkin were treated with CCCP for the indicated

human lens epithelial cell line; CCCP, mitochondrial protonphoric uncoupler

Protonophore carbonyl cyanide m-chlorophenylhydrazone (CCCP) depolarized

DiIC1(5) stain intensity decreases when cells are treated with reagents that

Oct 1, 2004 . Bcl-2 prevents loss of mitochondria in CCCP-induced apoptosis. de Graaf AO,

Aug 1, 2001 . Before application of CCCP, mitochondria were in the normal filamentous shape

CCCP causes quick mitochondrial membrane depolarization, greatly reducing

Feb 4, 2011 . CCCP dissipates the mitochondrial membrane potential, resulting in recruitment

Bax is not mobilized to mitochondria under these conditions. However,

Jun 23, 2009 . CCCP is therefore accelerating the working rate of the ETC, resulting in an

Mitochondrial import depends on ATP. By using an uncoupler like CCCP, we can

CCCP directly interferes with mitochondrial function and induces apoptosis. We

Where indicated, 10 ng valinomycin per mg protein and 1 u>1 CCCP was added.

The CCCP affects the protein synthesis reactions in seedling mitochondria.

Effects of CCCP-induced mitochondrial uncoupling and cyclosporin A on cell

Nov 24, 2008 . Parkin accumulates on impaired mitochondria. (a and b) HEK293 cells treated

It is known that in the presence of CCCP the carriers of the mitochondrial

Jun 15, 2006 . (D) The indicated constructs were transfected to HeLa cells, and cultured with or

Jun 12, 2011 . To date, the use of mitochondrial toxins, for example, 1-methyl-4-phynyl-

µM cccp rapidly induced a reduction of ∆ψm and ≥30 µM cccp induced a

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